After researchers discovered another colon cancer gene, the second so far, they concluded that they have found the causes of over 90 percent of the disease in its inherited form.
Every year 156,000 people are diagnosed with colon cancer and six of those cases are caused by those two genes together. In the same time, around 30 percent of non inherited cases are caused by these two genes of colon cancer.
It is expected that in the near future researchers will come out with some new tests to identify the presence of these genes in an individual and if either one of these is found, doctors can do tumor checks more frequently permitting them to discover them earlier while they can still be surgically removed. With this new knowledge it is assumed that over 90 percent of all that cases caused by inherited colon cancer can be evoited. MAY 2-8: Millions at Risk; Scientists Identify A Gene That Causes :: href=http://query.nytimes.com/gst/fullpage.html?res=9F0CE4DE163FF93AA35756C0A965958260 class=l onmousedown=return clk(this.href,,,res,37,)>MAY 2-8: Millions at Risk; Scientists Identify A Gene That Causes About 65 percent will develop colon cancer. of Helsinki in Finland, estimate that at least 13 percent of all colon cancers are caused by the gene. http://query.nytimes.com/gst/fullpage.html?res=9F0CE4DE163FF93AA35756C0A965958260HOME |
Researchers are confident that this new discovery will lead to new anticancer drugs in a very short time period, a period of two to five years. Association Between Biallelic and Monoallelic Germline MYH Gene :: href=http://jnci.oxfordjournals.org/cgi/content/abstract/96/21/1631 class=l onmousedown=return clk(this.href,,,res,63,)>Association Between Biallelic and Monoallelic Germline MYH Gene These two MYH gene mutations may account for a substantial fraction of Increased frequency of disease-causing MYH mutations in colon cancer families http://jnci.oxfordjournals.org/cgi/content/abstract/96/21/1631HOME | INHERITED SUSCEPTIBILITY TO COLORECTAL CANCER - Annual Review of :: href=http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.med.56.061704.135235 class=l onmousedown=return clk(this.href,,,res,124,)>INHERITED SUSCEPTIBILITY TO COLORECTAL CANCER - Annual Review of Polyps present at an average age of 16 y (range 7–36) and colon cancer at an Almost all cases of FAP are caused by germline mutations of the APC gene on http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.med.56.061704.135235HOME |
The genes are found on different chromosomes, but both of them act almost in the same way, being just like a guardian checking every new piece of synthesized DNA to make sure that no mutations appeared. But, if one of these genes is corrupted the new synthesized DNA pieces will be altered really bad and you will develop cancer as a result. Usually inherited cancer appears at the age of 50.
Thanks to these new discoveries new screening tests will be available for the general population. Most specialists agree that this is a huge step for the medical science resulting in the saving of countless lives and a great cost reduction in the medical system. colorectal cancer « www.cancer-genetics.com:: href=http://cancergenetics.wordpress.com/category/colorectal-cancer/ class=l onmousedown=return clk(this.href,,,res,82,)>colorectal cancer « www.cancer-genetics.comLynch/HNPCC syndrome is caused by germline mutations in genes that oversee DNA mismatch Posted by ramunas in HNPCC, cancer genetics, colon cancer, http://cancergenetics.wordpress.com/category/colorectal-cancer/HOME |
One of these genes is present in about 1 every 200 people all around the world making it the number one genetic defect. Screening will save a huge amount of lives but researchers already raise economic concerns regarding the medical health care; it may be possible that future agencies will deny the right to a health insurance just on the reason that a client presents a higher risk because he has one of these genes.
For more resource on different colon cancer subjects please click this link http://www.colon-cancer-center.com. You can also find valuable information about metastatic colon cancer or even about colon cancer treatment
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